Antimicrobial Activities of Seed Extracts of Mango (Mangifera indica L.)

Amgad A. Awad El-Gied, A and Martin R. P. Joseph, P and Ismail M. Mahmoud, M and Abdelkareem M. Abdelkareem, M and Ahmad M. Al Hakami, M and Mohamed E. Hamid, E (2012) Antimicrobial Activities of Seed Extracts of Mango (Mangifera indica L.). Advances in Microbiology, 2 (1). pp. 571-576. ISSN 10.4236

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Abstract

Mangifera indica L. is a species of mango in the Anacardiaceae family. It is found in the wild in tropical regions and cultivated varieties have been introduced to other warm regions of the world. This present study aimed to investigate the in vitro antimicrobial activities of methanol and ethanol extracts of mango seed against 25 representatives gram positive, gram negative, acid fast bacteria and fungi. Mango fruit seed were extracted by Soxhlet using methanol and ethanol as solvents. The extracts were tested against the microorganisms using disc diffusion method at different concentrations: 5 mg/mL, 3.75 mg/mL, 3.125 mg/mL, 2.5 mg/mL, 1.875 mg/mL and 1.25 mg/mL). In vitro antibacterial activities of methanol and ethanol extracts of mango bulb showed inhibitions to tested organisms with variable inhibition zones. Except one organism (Rhodococcus equi), no resistance among the tested strains was shown. The mean zone of inhibi￾tion produced ranged between 5 mm and 18 mm with 18 mm/Mycobacterium smegmatis showed the highest zone of inhibition. In most test strains comparable zones of inhibitions were noted for both methanol and ethanol extract. Can￾dida albicans and Aspergilllus niger were both inhibited by the extracts. The methanol and ethanol extracts of mango seed showed good inhibitory effects against almost all tested strains. The inhibition zones produced by mango extract were less than those produced by standard positive control drug. This could be due to low diffusion rate of mango ex￾tract in agarose medium, a thing needed to be further investigated. The products are potential new antimicrobial therapy in the ethnopharmacology domain.

Item Type: Article
Subjects: Medical laboratory
Pharmaceutical Sciences
Pharmacist
Divisions: College of Pharmacy > Pharmaceutical Sciences
Depositing User: Amged Algied
Date Deposited: 13 Apr 2017 11:22
Last Modified: 13 Apr 2017 11:22
URI: http://eprints.kku.edu.sa/id/eprint/588

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