BACTERIAL RESISTANCE OF ANTIBIOTICS USED IN URINARY TRACT INFECTION

KHALED.M. ALAKHALI, M and ABDULKARIM.K.ALZOMAR, K and SIRAJUDEEN S. ALAVUDEEN, S and NOOHU ABDULLA KHAN1, A and SAM ALI DAWBAA2, A BACTERIAL RESISTANCE OF ANTIBIOTICS USED IN URINARY TRACT INFECTION. Asian J Pharm Clin Res, 6 (1). pp. 1-5. ISSN 0974-2441

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Abstract

The antibiotic resistance is a global problem and requires taking measures to combat this growing problem. One example is by quantifying prevalence of resistant pathogens. Our aim was to define the prevalence patterns of resistance to antibiotics among urinary tract infections by carrying out an appreciable survey in the medical laboratories department, Al-Thawra hospital, Sana’a city.The work was performed retrospectively as a cross-sectional descriptive study, gaining the required information from the patient’s records in the medical laboratories.The results indicated that Escherichia coli was the most leading cause of urinary tract infections with 107 (52.2%) isolates followed by Pseudomonas aeruginosa with 39 (19%) isolates. Other species were Staphylococcus spp., Klebsiella spp., Proteus spp., and rarely Serratia and α-hemolytic Streptococcus spp.. The resistance pattern observed for these isolates, showed high resistance rates to the β-lactam antibiotic ampicillin and low rates to the aminoglycoside antibiotics gentamicin and amikacin. The resistance rates to trimethoprim-sulphamethoxazole, nalidixic acid and cefotaxim were also high. The uropathogens developed a moderate average resistance rates to ciprofloxacin and nitrofurantoin.

Item Type: Article
Subjects: Pharmacy
Divisions: College of Pharmacy > Pharmacy
Depositing User: KHALED ALAKHALI
Date Deposited: 27 Apr 2017 09:27
Last Modified: 27 Apr 2017 09:27
URI: http://eprints.kku.edu.sa/id/eprint/724

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