BENEFITS AND PITFALLS OF USING INSULIN IN THE MANAGEMENT OF TYPE 2 DIABETES PATIENTS: A CLINICAL EVALUATION

S.alavudeen, Sirajudeen. and C.K, Dhanapal and M.AL AKHALI1, KHALID and Abdulla Khan, Noohu and V.V., Venkatachalam (2014) BENEFITS AND PITFALLS OF USING INSULIN IN THE MANAGEMENT OF TYPE 2 DIABETES PATIENTS: A CLINICAL EVALUATION. J App Pharm, 6 (4). pp. 416-426. ISSN 19204159

[img] PDF
BENEFITS AND PITFALLS OF USING INSULIN IN THE MANAGEMENT OF TYPE 2 DIABETES.pdf

Download (1MB)
Official URL: http://www.www.japharmacy.ca

Abstract

Introduction: Type 2 diabetes is associated with a range of cardiovascular risk factors. Insulin therapy has several metabolic benefits. However, large doses of insulin are often required to achieve near normal blood glucose levels and are associated with weight gain and the risk of hypoglycemia. Objectives: To evaluate the efficacy and safety of insulin monotherapy in type II diabetes patients whose glycemic control was not maintained by the oral hypoglycemic agents (OHAs). Methods: single-centre, observational retrospective study conducted at Asir Diabetes Center from June 2012 to June 2013 evaluating the efficacy and safety of the insulin monotherapy in type 2 diabetics. Results: At study end, the mean HbA1c value was reduced from 9.7± 2.2 % to 8.4± 1.5 %. FBG was decreased from 183.7± 73.02 mg/dl to 183.7± 73.02 mg/. 14.5 % of patients achieved HbA1c ≤7%. 27.5% of patients achieved the target fasting blood glucose level (≤110 mg/dl). 34.8% of patients had confirmed hypoglycemia. Conclusion: Insulin monotherapy therapy has shown significant reduction in the HbA1c value, fasting plasma glucose level, post prandial glucose level and lipid levels and thereby a reduction in the long-term complications of diabetes.

Item Type: Article
Subjects: Pharmaceutical Sciences
Divisions: College of Pharmacy > Pharmaceutical Sciences
Depositing User: SIRAJUDEEN Shaik
Date Deposited: 14 May 2017 21:22
Last Modified: 14 May 2017 21:22
URI: http://eprints.kku.edu.sa/id/eprint/875

Actions (login required)

View Item View Item