The ameliorative effects of Averroha carambola on humoral response to sheep erythrocytes in non-treated and cyclophosphamideimmunocompromised mice

Shadma, Wahab and Arshad, Hussain and P., Ahmad and aleza, rizvi (2014) The ameliorative effects of Averroha carambola on humoral response to sheep erythrocytes in non-treated and cyclophosphamideimmunocompromised mice. Journal of Acute Disease. pp. 115-123.

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Abstract

Objective: To evaluated immunomodulatory and antioxidant activity of the methanol extract of Averrhoa carambola (A. carambola) leaves in mice. Methods: The assessment of immunomodulatory activity on specific and non-specific immunity was studied of test extract by oral feeding canula to the test groups. Hemagglutinating an btiyb oaddym i(HniAst)r atittieorn, dpeerla oyxeidd attyipone (oLfP hOy),p reerdseuncesidt igvliutyta (tDhTioHn)e r(eGsSpHon), sseu, pheeromxaidtoel odgiiscmaul tparsoef i(SleO D(H),b c, aWtaBlaCs,e R(CBACT),) lwipeirde determined by in vivo experiments. Results: The evaluation of immunomodulatory potential of A. carambola (800 and 1 200 mg/kg, p.o.) evoked a dose-dependent increase in antibody titer values and DTH reaction induced by SRBC was also found significant (P<0.001). Also it caused iinnc creyacsloep ihno hspemhaamtoildoeg-icianld purcoefdil ei,m GmSuHn, oSsOuDp,p CreAsTse adc tmiviictye . aRndes suilgtn sifhiocwanst ltyh adte cthreea esexdtr aLcPtO t rleeavteelds aanreim baelisn sgh uowseedd ausp areng uadlajtuiovna notf i(InL -co6 nadnidti oTnNsF -of毩 im) cmyutonkoidneefsi.c Cieonncyc luins icoannsc: eIrm amnudn otom ao dluimlaittoerds extent in acquired immunodeficiency syndrome. The results obtained in this study indicate that A. carambola possesses potential immunomodulatory and antioxidant activity.

Item Type: Article
Subjects: Pharmaceutical Sciences
Pharmacy
Divisions: College of Pharmacy > Pharmaceutical Sciences
College of Pharmacy > Pharmacy
Depositing User: SHADMA WAHAB
Date Deposited: 23 Aug 2017 08:48
Last Modified: 23 Aug 2017 08:48
URI: http://eprints.kku.edu.sa/id/eprint/964

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