Pharmacokinetic of simvastatin study in Malaysian subjects

Khaled Alakhali, K and Yahaya Hassan, Y and Nornisah Mohamed, N and Mohd Nizam Mordi, M (2013) Pharmacokinetic of simvastatin study in Malaysian subjects. IOSR Journal of Pharmacy, 3 (1). pp. 46-51. ISSN 2319-4219

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The pharmacokinetic of simvastatin 40 mg tablet was assessed in 9 healthy Malaysian male subjects after a single oral dose in Pinang Hospital, Malaysian. Blood samples were collected at specified time intervals, plasma separated and analyzed for simvastatin using validated LC-MS-MS method at unversiti sains Malaysia. The pharmacokinetic parameters AUC0-24 Cmax, Tmax, t1/2, Ke, Cl and Vd were determined from plasma concentration-time profile for simvastatin. The results of this current method were consistent with other methods previously reported.

Item Type: Article
Subjects: Pharmacy
Divisions: College of Pharmacy > Pharmacy
Depositing User: KHALED ALAKHALI
Date Deposited: 23 Aug 2017 08:52
Last Modified: 23 Aug 2017 08:52

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