Comparative evaluation of transdermal diclofenac patch and oral diclofenac as an analgesic modality following root coverage procedures

Tejaswi Venkat Devireddy, Devireddy Venkata Tejaswi and M.L.V. Prabhuji, M.L.V. Prabhuji and Shaeesta Khaleelahmed Bhavikatti, Shaeesta Khaleelahmed B (2014) Comparative evaluation of transdermal diclofenac patch and oral diclofenac as an analgesic modality following root coverage procedures. Comparative evaluation of transdermal diclofenac patch and oral diclofenac as an analgesic modality following root coverage procedures, 62 (4). pp. 68-71. ISSN 0363-6771

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Abstract|ملخص البحث

Diclofenac sodium is a nonsteroidal anti-inflammatory drug and is effective in the management of pain following periodontal surgery. However, oral administration of diclofenac can lead to gastrointestinal (GI) complications. To overcome these drawbacks, diclofenac is formulated as a transdermal patch, which delivers the drug into systemic circulation through skin. Twenty patients were selected for root coverage procedures with subepithelial connective tissue grafts bilaterally. Following the surgical procedure on the control sites, oral diclofenac sodium 100 mg was administered QD for 3 days. Following the surgical procedure on the contralateral test site, a transdermal diclofenac patch (TDP) was applied every 24 hours for 3 days. The TDP was effective in postoperative pain control following root coverage procedures with subepithelial connective tissue grafts. Pain tolerance was higher with the TDP as compared to oral administration, as it did not cause any GI complications.

Item Type|تصنيف النتاج العلمي: Article| منشور علمي
Subjects | مجال موضوع النشر: Dentistry
Medicine and Surgery
Divisions | الكلية: College of Dentistry > Dentistry
Depositing User: DR. SHAEESTA KHALEEL AHMED BHAVIKATTI
Date Deposited: 16 Feb 2018 15:39
Last Modified: 16 Feb 2018 15:39
URI: http://eprints.kku.edu.sa/id/eprint/3381

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