Effect of Fenugreek Seeds Against Irradiation-Induced Oxidative Stress in Adult Rats

Alrasheedi, Amani and Al-Aamri, Sarah and Eassawy, Mamdouh and Bawazeer, Fayza (2016) Effect of Fenugreek Seeds Against Irradiation-Induced Oxidative Stress in Adult Rats. World Journal of Dairy & Food Sciences, 11 (1). pp. 37-51. ISSN 1817-308X


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Abstract|ملخص البحث

The present study aims to evaluate the beneficial effect of fenugreek seeds against Irradiationinduced oxidative stress in adult rats. Forty-two healthy adult male Wister rats were divided into four groups: normal control, irradiated control, pre-treated irradiated group and pre and post-treated irradiated group. Results showed significant increase (P<0.05) in liver relative weight in irradiated control group after one and fourteen days post-irradiation compared to normal control group. Feeding rats with fenugreek 5% showed significant (P<0.05) decrease in the liver relative weight of the two groups (Pre-treated irradiated and pre and post-treated irradiated) compared to irradiated control group. Exposing rats to irradiation showed significant (P<0.05) increase in the level of liver enzymes (AST, ALT and ALP) in irradiated control group after fourteen days post irradiation. Regarding the changes occurred in antioxidants enzymes in liver tissues, a significant (P<0.05) decrease (GSH & SOD) and increase in (LOP) in irradiated control group. There were significant (P<0.05) increase in GSH & SOD levels of Pre and Post-Treated Irradiated group at both one and fourteen days post irradiation. In irradiated rats, exposure to radiation caused severe liver damage including hepatocyte edema, necrosis of the hepatocytes, karyolysis, proliferation of kupffer cells and dilated sinusoids.

Item Type|تصنيف النتاج العلمي: Article| منشور علمي
Subjects | مجال موضوع النشر: Medical laboratory
Public Health
Public Nursing
Radiological Sciences
Divisions | الكلية: College of Administration and Home Economics - Abha > Home Economics
Depositing User: Sarah Alamri
Date Deposited: 11 Mar 2018 14:07
Last Modified: 11 Mar 2018 14:07
URI: http://eprints.kku.edu.sa/id/eprint/3503

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